It does depend upon the water and grist. There could be cases where adding minerals to the mash would be counterproductive. So its not so easy to just say...add them all at once. Since the OP indicates that they start with RO water, there could be cases where a bit of alkalinity needs to be added. If they are step infusing, then adding all the alkalinity producers at once could really throw off the mash pH.
There are only a few styles that benefit from step mashing. Looking at one of the most extreme cases would be the typical Hefe in which you might start with a rest in the 110 to 125F range and then want to boost it to the 150F range. That step infusion could approach the original mash in volume. That will definitely throw off the water chemistry.
In the case of stepping from just a Beta rest temp to an Alpha rest temp, the infusion volume is probably minor. Then I can agree that throwing all the minerals in wouldn't be a big deal.