Only at the lab on 3 ml cultures. The biggest centrifuge I know about in our building will handle maybe 250 mls per container. Here is a pic of the inside of one of those that broke - good thing the outside remained intact while the inside shredded itself. The size of centrifuge you would need to pellet yeast in a 5-gallon batch . . .My old boss was a mechanical engineer who previously worked for Dupont designing centrifuges. He told me stories about doing this on purpose to test the housings. Fun!