don't worry about the HEPA filter when using O2. Pure O2 is extremely toxic under long exposure and is essentially self sterilizing.
Kai
I was thinking more about dust, metal particles, grease, etc.
I'm sure it's overkill, but the filter was only 10 bucks, and it's rated for 120 hours of use (which is enough to oxygenate a couple thousand 5 gallon batches).