A guy I knew from college is a custom bicycle framebuilder. I think you can take what he says about framebuilders, and just insert "nano-brewers." The barriers to entry are lower than for brewing, so the fail rate is higher, but a lot of the same pitfalls await both.http://waltworks.blogspot.com/2013/01/burnout-or-why-framebuilders-dont-last.html
"Start with 100 new framebuilders, all beady-eyed and eager to build bikes.
-Of our builder population, let's say:
20% are recent college graduates or dropouts living with their parents/roommates.
30% are naturally terrible at making things out of metal when they start (I was one of these).
50% don't remember trig from high school and think building good bikes is all about pretty fillets or Justin Bieber's initials carved into stainless lugs.
75% have no startup funds and have to order tubesets one at a time, file miters by hand, and work out of an unheated garaged (again, me).
80% have never run a business of any kind and are unable/unwilling to use math to figure things out - like how much money to charge, or what their costs are.
100% will sometimes screw stuff up, and 50% (or more) think they are perfect and won't accept blame for anything going wrong with a frame (whether it's a cracked tube, geometry not quite right, whatever) and will slowly (or quickly) accumulate angry customers. "