I envy some of the shorter rinse/switch out practices mentioned here. Most of my beers leave too obvious deposits in my lines for me to do anything less. None of my brews are cold crashed or filtered and all but the longer-aged, clarified ones need the PBW/LLC one two punch. I haven't tried a sole LLC cleaning for keg and lines.
So plenty of people just use PBW/oxy and the lines go completely clean? Even with very hot PBW flushed and held for 20-30 mins there are still some beer lines with holdout globule deposits. Line age and quality is not the issue; even on first use there were stubborn deposits remaining just past the QD.