If you can head out to Ocean Beach one night, I'd highly recommend it. Pizza Port brewing is right off the beach, and they have several excellent beers on tap and pretty good pizza. There's also a few bottle shops in that area, and you can walk out on the pier for free.
I just returned from a business trip and went to Stone Liberty Station, Lost Abbey/Port Brewing, White Labs, Modern Times, but I had the best time at Pizza Port. I ended up going there three nights. I liked their Shark Attack and O'Behave DIPA. They also had Pliny on tap, so maybe you'll get to hit that up too when you're out there.