I just made 10 gallons of a 67 IBU 1.065 American IPA and split it between (2nd gen.)1450 and US05. There is a stark contrast between the two. I prefer the 1450 in every respect and had several friends agree. The US05 seemed thinner and less malty but had a little higher attenuation so that may account for that. The mouthfeel is definitely smooth and creamy with the 1450 and the hop flavor seemed to complement the beer more. It made a bolder and richer beer IMO. I have no intention of using US05 again for an APA/IPA. I split different yeast strains between batches nearly every time I brew and I cannot stress enough that yeast makes beer, not recipes.