I have 6 lbs of whole cone centennial hops, that were given to me very recently, that I vacuum sealed and froze 12 - 20 hrs after they were picked, and til then kept cold, dry and in the dark in paper bags. I plan to use them for Sean Terrill's Two Hearted Ale Clone. After reading this thread, I'm thinking it might be wise to open what I figure I'll need and dry those on a screen prior to using them. And for the bittering addition I'll use some pelletized centennials I have in the freezer.
Last year I used a bunch of half-dried whole cone cascades for flavor and aroma additions in a beer along with other varieties of pellet hops and it came out great, although higher IBUs than I expected.
I noticed a comment or two in this thread that has me wondering if part of the deal is individual tastebuds rather than science-based failures from using fresh hops. I mostly have tried commercial versions of "fresh-hopped" beers and typically enjoyed them, and noticed mainly that they had less pronounced bitterness than a standard similar beer, kinda like what you get from FWH with dried hops.
I guess I also experienced a more flowery, fresh, rounded pungency from the wet-hopped beers.