Looking at my last IPA spreadsheet from Bru'NWater, following Martin's suggestions regarding the "Pale Ale" profile, my Ca was 140, Mg 0+whatever may have been in my RO, Sulfate was right at 300 and pH at 5.4. I loved this brew, hops were brilliant. My additions to the RO were: gypsum, canning salt, CaCl, and 1g baking soda to get to 5.4. No epsom at all. YMMV, but it worked for me
Edit: further review shows that the batch I loved so much had the same specs except pH was 5.25, the numbers i gave above were for the updated version I plan on brewing soon. I dont know how much changing the pH from 5.25 to 5.4 will change the outcome, with the only addition being the baking soda to raise bicarb and thus pH. My Na will also be a little higher. I will know when I brew it again, but it was Martin's suggestion to target that 5.4 for hoppy beers, so I will be giving it a try. If I dont like it as much, I still have the old spreadsheet with pH of 5.25. Dont know if this helps or not, but it does give me a point to observe in my own practices