I tend to think of 20 min and later additions in terms of weight as opposed to %alpha. IMO, all other things being equal, the freshness of the hops tends to drive flavor and aroma levels more than alpha, IMO. In other words, an oz at 15 of one alpha tends to smell and taste pretty close to the same as an oz of the same varietal at 15 of a different alpha, provided they are about the same freshness (and the same form - pellets vs whole), with pellets yielding the most consistent flavor/aroma. If the recipe calls for an oz at 15, that's what I add. I won't adjust it for alpha. I make the adjustment by varying the amount of bittering hops to achieve the overall target IBU levels.
Essentially, I calculate the bittering addition amounts by working backwards in the boil. I first calculate IBU contributions of the 20min and later additions, and then figure out the amount needed for the boil addition so the total hits the overall target IBU level. This may even mean moving a small addition to 55 or 50 if the alpha of the bittering hops I have on hand is too high for a 60 min addition to hit the target.
Hope this makes sense.