I gave up on my prism refractometers and splurged on a Milwaukee Digital MA871. I get much more accurate readings (I think). With unfermented wort - it appears to be accurate to my hydrometer, but with dark beers not so much.
I use it during sparge and during fermentation, but not looking for FG, rather stable readings over several days. I still use a calibrated hydrometer for actual OG and FG. It is usually very close for OG, but I tend to use the hydrometer sample for a fast ferment test anyways.