I'm of the opinion that an IPL needs to taste like a lager or else it's just a regular IPA, regardless of the yeast. So Mexican Lager is out for me since it doesn't add any real lager character. Same thing with US 2-row. I've been happy with Pils malt and 34/70 as a base in my hoppy lagers. WY2633 has worked pretty well, too.
Currently, I have a hoppy lager fermenting with 2278. I haven't brewed with that strain before, but I've heard it produces a very crisp beer, so I have high hopes.
As far as specs are concerned, I'd target the same OG as an IPA. For IBUs, I like the lower end (maybe 50-60) so the bitterness doesn't completely overwhelm the malt and yeast character. For hops, I like at least a little noble character. Fruity noble variants like Sterling, Motueka, and Mandarina Bavaria are good choices to build around. From there you can splash in the usual pine/tropical/citrus as you like.