Yes, I do this a lot. Rather than doing a 50/50 blend, I like to use up one and make up the rest with the other. Take your pick.
Randy Mosher in his book Radical Brewing also advocated blending to build complexity. He suggests thinking about ingredients as a spectrum, much like a portrait artist would blend different hues of paint on their palette to create the hue that he or she wants, rather than just using globs of one thing and another. Either will work but it depends what you want. If you spread things out you also ensure you'll hit the target. For example, a beer with just 2-row and Crystal 40 is not going to be as complex as 2-row, Maris Otter, Crystal 20, 40, and 60. It's more the shotgun approach than the sharpshooter, but it's another thing worth trying.