In my most humble opinion, the very best beercation destination for the entire family would be Astoria Oregon.
During the daytime, the family can check out the local scene including climbing the Astor Column, enjoy Seaside, the beach and Fort Stevens State Park, and much more. But during the evening for the adults there is a good variety of incredibly good beer stops to check out. Most of which you can walk between. Or take the trolley that runs along the waterfront.
There's Rogue out on the pier, The Wet Dog Saloon, an aspect of Astoria Brewing, Desdemona, also of Astoria Brewing, Hondo's, Fort George in the historic building with the incredible view, and last but not least my personal favorite Buoy Brewing, right on the waterfront with the sea lion viewport in the floor of the main dining room. Every one of these brew houses make some of the best beer you'll find anywhere.
If you're living anywhere from Seattle to Eugene and looking for a great escape, this is it.