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Are you guys talking a real APA, with real guidelines of IBUs or are you suggesting a Three Floyds Alpha King APA=American IPA. I think a 35-40IBUs 5.8-6.2% SMaSH APA would not be terrible, but simcoe is a strong hop in my opinion.
Columbus is NOT neutral.Magnum is great, and quite neutral.Perle and Hallertaur are other good clean hops for this sort of thing.IMO, Perle is a very under-appreciated hop with some great properties.