I have only been to Holy City and the beer was very good and a cool tasting area with garage doors that opened up to the outside seating, games area. I have also had some Westbrook beers and they were also very good, but I have not been to their brewery. My wife and I will be heading down to Isle of Palms and Charleston in late July, so if you have any other recommendations from your visit, I would like to hear once you get back. Enjoy your trip to Charleston, it is a really charming city and we love it every time we go to visit family there. Also, depending on the time you have, I would suggest taking a day trip to Savannah, GA, which is about an hour away.
Cheers!
Mark