Just as an example of how mutating Yeast would work.
There is UVA and UVB light, so a good method of mutation would be to make 3 identical batches of propagating Yeast in 1 Gallon or 6 Gallon Glass Carboys, and have one with UVA light, one with UVB light and one with both. Then do different combinations of mixing them, and switching them to new light, etc. And make new batches and try different combinations. Then add amino acids, and DNA from plants.
Then mix the mutated Yeast with other Yeast strains, and go through the process again.