I've only been to one brewery in San Diego (Modern Times Lomaland), but thinking back to the people who showed up to pronight at NHC.
Down in Miramar, near Mikkeler and White Labs, Mike Hess and Alesmith are right next to each other. I've always had good stuff from Alesmith, and I remember Mike Hess from NHC and it was pretty good.
St Archer is in that area too. They are MillerCoors, so do with that what you will.