One fascinating insight I've had from doing warm pressure fermentation of lagers is that we've probably been misinformed regarding the importance of cool temperatures early on, and exactly where in the fermentation process ester production occurs. We've been told that lagers need to be cold early on, and that it doesn't matter as much if temperature increases later, because it's the early stages that determine ester levels. But in pressure fermentation, as used even in German commercial practice, you are both starting and fermenting the lager at ale temperatures , and applying head pressure as late as 50% of the way to final attenuation in order to suppress ester formation. So it would logically follow that, as either low temperature or high pressure may be employed to suppress ester formation, and at least one of these can work when implemented later, not earlier, in the process, the critical time for either measure must be after active fermentation has commenced, not before. So I conclude that it should be acceptable procedure to pitch lager yeast at a temperature at least up through the 60°'s Fahrenheit, and cool the fermenter through the lag phase and up to high kräusen. Anecdotal evidence from many homebrewers supports this conclusion. Should I ever do a non-pressurized lager fermentation again, I would probably do this. It gets your yeast pitched and your brew day wrapped up sooner, and should allow for more yeast growth at the warmer temperature during the lag phase, making up for any deficiency in your pitch rate. I suspect that while some factors for esters are produced during the lag and low kräusen stages, actual ester synthesis occurs later; after all, esters are made up of an alcohol and a fatty acid, so while the fatty acids may be present earlier, alcohols must be produced during fermentation, and maybe thereafter we can still regulate the process of ester formation. At least that's my emerging surmise, with the huge caveat that I'm an experienced brewer, but that's where most all of my knowledge of microbiology and the related chemistry comes from. I would really like to hear from someone with actual formal knowledge regarding this matter.