Every few months I do an extended (2-4 hours) hot water and alkaline cleaner re-circ of my HERMS and counterflow chiller to be sure nothing too nasty is lurking on the interior of the pipes and to help assure that I am getting good cooling efficiency without beerstone - but I use a stainless system, so I don't have the copper green issues....then maybe once a year, I will follow up with an extended starsan recirc after thoroughly rinsing out the alkaline cleanser.