I think that depends on the fermantable(s), efficiency of your system, the batch volume, and the style of beer you want to brew.
If, for example, you want to brew 5 US gal of a Pale Ale, 6(.6) lbs of grain probably won’t get you to the minimum OG that is normally associated with the style. If you used 6 (.6) lbs of grain you’re going to need some other fermentables (sugar, DME, LME, etc) to accompany it.
On my system I am usually in the 12# range of grain bill for 5 gal batches of the all grain styles I enjoy. I rarely use DME or LME but have used several types of sugar (turbinado, candi syrup, molasses, etc).
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