I've been brewing for ... uh ... over 20 years. Here is my best improvements and some people will say I'm full of s***ake mushrooms. And this stuff can happen over time and not necessary. I've brewed on everything. HERMS. RIMS. 3 tier. single tier. BIAB. MIAB.
1. Make sure all of your barbs and clamps are the same size.
2. If you don't have quick disconnects, find a 4 in 1 screwdriver and take the bits out to find one that fits the hose clamps you use. Or better yet, get the thumb screw ones. But I use the home depot clamps with the my 4 in 1 driver without the bits and I am gold.
3. don't drink until you finished.
4. You can't oversanitize but you can undersanitize.
5. keep oxygen out on the cold side as best as you can.
6. control your fermentation temp.
7. YOUR WATER QUALITY MATTERS. A LOT. If you think you need to filter it, go RO or distilled.
this list goes on forever.
8. I've made starters, vitality starters, 2 liter starters, 1 liter starters, etc. If you aren't making an Imperial something, dry yeast works great. and even then, pitch 2 packs of dry yeast.
9. Make your system works for you and don't try to do what commercial guys do.
That's all I got.