I am very fond of Simcoe, Ahtanum, and Amarillo ala Surly Furious. Another combo that I like is, Simcoe, Centennial, and Amarillo. I haven't had a chance to use some of the new citrusy varieties like Sorachi Ace or Citra, so I will likely experiment with them this year also in my APA/IPA's.
I am going to do a couple of single hop IPA's to start 2011 with a Two Hearted clone and an all Chinook IPA, and possibly an all Summit that is similar to Griffin Spit (I am intrigued by the tangerine flavor).
J