Hey Danny, name all those dry counties that exist today...actually, I'll do it for you, one, Graham, and it is way up in the mountains. 99 other counties which aren't dry, of course not all have craft beer at the ready, but the availability gets better every single day.
Tom, your problem is going to be many breweries do not bottle at all. They may have growlers, but your shelf life is not extended. Most of the one offs come with long lines and big release parties. Like Foothills Sexual Chocolate, try finding a bottle of that outside of the release party, heck, it's pretty rare to find it on draft two weeks after release.
With that in mind, send your brother to Sam's Quick Shop in Durham. It looks like a gas station from the outside so don't be put off.http://samsquikshop.com/
If your brother goes to Ashvegas the beer store to hit is Bruisin Ales. To add insult to injury they have zero parking spaces (yep, not even one) so finding a place to park is challenging. Most of their wares are Belgian, but they do tend to carry the one-offs which are bottled from the Asheville area breweries. http://www.bruisin-ales.com/
The list of breweries in the Asheville proximity is very good, but getting their wares might require a trip to each brewery. Pisgah, Green Man, Wedge, Highland, French Broad, Lexington Avenue, Asheville Brewing, Oyster House, and Appalachian. Not too far away are Nantahala, Heinzelmannchen, Catawba and Olde Hickory. Then a little further down the hill in Winston-Salem is Foothills (growlers only - for now).
Looking at the Triangle area -
Now what to look for - when exactly in a few months? The Anniversary beer from Carolina will be out the first week in July. The site says it will be an Imperial IPA and the special releases are pretty good. It will only be available at the brewery and will probably sell out in two to three weeks. http://www.carolinabrew.com/
Big Boss doesn't currently bottle any of the one-offs, but he could grab a fresh growler at their tap room, Horniblows Tavernhttp://bigbossbrewing.comhttp://bigbossbrewing.com/tap-room.aspx
LoneRider bottles are out and about. Might be able to get a growler at the breweryhttp://www.loneriderbeer.com/
Triangle is canning and he could grab a fresh growler at the breweryhttp://www.trianglebrewery.com/
Fullsteam has growlers at the brewery (no bottles)http://www.fullsteam.ag/
The more pedestrian Natty Greenes offerings are available out and about bottled, but you'd need to go to the brewpub for something more interesting and again it would be a growlerhttp://www.nattygreenes.com/content/natty-greenes-pub-brewing-co-raleigh
I'm pretty sure Roth has growlers, but I have not actually had anything from them yethttp://www.rothbrewing.com/home.shtml
Aviator has growlers at their tap roomhttp://www.aviatorbrew.com/
Mother Earth is down east in Kinston, but you should find bottles at Sam'shttp://www.motherearthbrewing.com/
Duck-Rabbit should be able to find at Sam's, all their seasonals are bottled with the exception of the very rare Paul's Day Off which has already come and gone.http://www.duckrabbitbrewery.com/
Mash House can be had in growler at some of the restaurants like Twisted Forkhttp://www.themashhouse.com/
In Greensboro Red Oak. Their standard beer is kinda boring as is Hummingbird, their Battlefield Bock is great, but I don't believe it is bottled and I'm not sure if they do growlers.
Any questions, lemme know.