I started with Iodophor. Years back, I had a persistent low level infection that wasn't ruing the beer, but definitely effecting the flavor. I switched to StarSan and it went away, so I've used StarSan for the last 10 years or so. But recently, I've switched back to Iodophor for the bulk of my cleaning. I've been traveling for business with a couple guys from National Chemical, who make BTF Iodophor. After talking to one of their chemists, it looked like Iodophor would do at least as good a job, if not better. I still keep a spray bottle of StaSan for instant use, but the bulk of my sanitizing is done with Iodophor.