Because of the excessive quantities of hops I use, the only efficiency I really bother with is pre-boil. I no-sparge in a cooler with a grain bag, and I give the bag a decent squeeze at the end (but don't wring it totally dry). I end up in the 81-82% range for my preboil efficiency for a 75 minute mash.
I don't normally worry about my mash thickness, but I notice that efficiencies start to dip for thin mashes approaching 4 qt/lb. For beers where the full volume mash would be thinner than 3.3-3.5 qt/lb, I keep it around 3 qt/lb and add the rest to the runoff pre-boil.